P21 Research Kit
P21 research kit. Includes a lyophilized peptide vial and accessory components for laboratory research preparation.
Purity-tested per lot. Intended for compound characterization, reference experiments, or laboratory training applications.
For laboratory research use only. Not for human or veterinary use.
$180.99
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Product Details
Characteristics
| Molecular Formula | C30H54N6O5 |
| CAS Number | 1174043-81-0 |
| Molar Mass | 578.79 g/mol |
| Amino Acid Sequence | Ala-Glu-Thr-Gln-Leu-Gln-His-Ser-Leu-Gly-Ala-Leu-Pro-Arg-Arg-Arg |
| Synonyms | P021, P21 |
| Solubility | Water-soluble |
| Organoleptic Profile | White powder |
| Composition | Synthetic peptide |
How does P21 work?
P21 exerts its effects through various mechanisms of action. As studied in P21 peptide spray research applications, one of the primary ways P21 functions is by promoting the survival and growth of neurons. Studies have shown that P21 can protect neurons from oxidative stress and apoptosis, which are common factors contributing to neuronal damage and degeneration.
Additionally, P21 has been found to enhance the effects of CNTF, a protein that plays a crucial role in the development and maintenance of the nervous system. By modulating CNTF signaling, P21 spray may help to support neuronal survival and function.
Furthermore, P21 has been investigated for its potential to stimulate the proliferation and differentiation of neural stem cells. By promoting the growth and development of new neurons, P21 may contribute to the regeneration and repair of damaged neural tissues. This property of P21 has garnered significant attention in the field of regenerative medicine, particularly in the context of neurodegenerative disorders.
P21 Peptide Spray Benefits
The potential benefits of P21 peptide spray have been explored in various research studies. One of the most promising applications of P21 spray is in the study of neurodegenerative disorders, such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS). By promoting neuronal survival and protecting against oxidative stress and apoptosis, P21 may help to slow down or prevent the progression of these debilitating conditions in experimental models.
In addition to its neuroprotective properties, P21 has also been investigated for its potential to enhance cognitive function. Studies suggest that P21 may improve memory and learning abilities by stimulating the growth and development of new neurons in the brain. These findings have significant implications for research into cognitive decline associated with aging and neurodegenerative disorders.
Moreover, P21 peptide spray formulations used in laboratory settings have shown promise in regenerative medicine research. By promoting the proliferation and differentiation of neural stem cells, P21 may contribute to the regeneration of damaged neural tissues. This property could potentially support the development of novel research strategies targeting spinal cord injuries, stroke, and other conditions characterized by neuronal damag
Side Effects
While P21 peptide spray has demonstrated numerous potential benefits in laboratory research, it is important to note that this P21 spray is currently intended for research purposes only. The safety and efficacy of P21 in mammals have not been fully established, and further studies are needed to assess any potential side effects or adverse reactions. As with any research compound, caution should be exercised, and appropriate safety protocols should be followed when handling and administering P21.
Summary
P21 (P021) is a promising synthetic peptide with the molecular formula C30H54N6O5. Research studies have highlighted the potential of P21 peptide spray in various therapeutic applications, particularly in the field of neuroscience. P21 has been shown to exhibit neuroprotective properties, promote neuronal survival, and enhance the effects of CNTF. Additionally, P21 has been investigated for its ability to stimulate the growth and development of new neurons, making it a candidate for regenerative medicine approaches.
While the benefits of P21 peptide spray are numerous, further research is needed to fully understand its mechanisms of action and assess its safety and efficacy in mammals. As a research compound, P21 holds significant promise for advancing our understanding of neurodegenerative disorders and developing novel therapeutic strategies.
References
- Kazim SF, Iqbal K. Neurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer’s disease. Mol Neurodegener. 2016 Jul 11;11(1):50. doi: 10.1186/s13024-016-0119-y. PMID: 27400746; PMCID: PMC4940708.
- Baazaoui N, Iqbal K. Alzheimer’s Disease: Challenges and a Therapeutic Opportunity to Treat It with a Neurotrophic Compound. Biomolecules. 2022 Oct 2;12(10):1409. doi: 10.3390/biom12101409. PMID: 36291618; PMCID: PMC9599095.
- Bolognin S, Buffelli M, Puoliväli J, Iqbal K. Rescue of cognitive-aging by administration of a neurogenic and/or neurotrophic compound. Neurobiol Aging. 2014 Sep;35(9):2134-46. doi: 10.1016/j.neurobiolaging.2014.02.017. Epub 2014 Mar 2. PMID: 24702821.
- Wei W, Liu Y, Dai CL, Baazaoui N, Tung YC, Liu F, Iqbal K. Neurotrophic Treatment Initiated During Early Postnatal Development Prevents the Alzheimer-Like Behavior and Synaptic Dysfunction. J Alzheimers Dis. 2021;82(2):631-646. doi: 10.3233/JAD-201599. PMID: 34057082; PMCID: PMC8385525.
- Liu Y, Wei W, Baazaoui N, Liu F, Iqbal K. Inhibition of AMD-Like Pathology With a Neurotrophic Compound in Aged Rats and 3xTg-AD Mice. Front Aging Neurosci. 2019 Nov 19;11:309. doi: 10.3389/fnagi.2019.00309. PMID: 31803044; PMCID: PMC6877482.
- Kazim SF, Blanchard J, Dai CL, Tung YC, LaFerla FM, Iqbal IG, Iqbal K. Disease modifying effect of chronic oral treatment with a neurotrophic peptidergic compound in a triple transgenic mouse model of Alzheimer’s disease. Neurobiol Dis. 2014 Nov;71:110-30. doi: 10.1016/j.nbd.2014.07.001. Epub 2014 Jul 15. PMID: 25046994.
- Silvia Bolognin, Mario Buffelli, Jukka Puoliväli, Khalid Iqbal, Rescue of cognitive-aging by administration of a neurogenic and/or neurotrophic compound, Neurobiology of Aging, Volume 35, Issue 9, 2014, Pages 2134-2146, ISSN 0197-4580, https://doi.org/10.1016/j.neurobiolaging.2014.02.017.
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